Search results for "large [Cosmology]"

showing 10 items of 272 documents

Clinical features, disease progression and use of healthcare resources in a large sample of 866 patients from 24 headache centers: A real-life perspe…

2021

Objective: To develop a dedicated Italian chronic migraine (CM) database (IRON project) to overcome disease misconceptions, improve clinical administration, reduce patients' burden, and rationalize economic resource allotment.Background: Proper CM management requires a comprehensive appraisal of its full clinical, social, and economic complexity.Methods: In this cross-sectional study, CM patients were screened in 24 certified headache centers with face-to-face interviews. Information on sociodemographic factors, medical history, characteristics of CM, and of prior episodic migraine (EM), and healthcare resource use was gathered using a semistructured web-based questionnaire.Results: A total…

AdultMalePediatricsmedicine.medical_specialtyDatabases FactualMigraine DisordersDiseaseregistryState Medicine03 medical and health sciences0302 clinical medicineChronic MigraineSurveys and QuestionnairesHealth caremedicineHumansMass ScreeningMedical history030212 general & internal medicinedatabaseEconomic complexitybusiness.industryDisease progressionhealthcareMiddle AgedPatient Acceptance of Health CareLarge sampleCross-Sectional StudiesNeurologyItalySocioeconomic Factorseconomic burdenDisease ProgressionResource usePain ClinicsFemaleSettore MED/26 - NeurologiaNeurology (clinical)chronic migrainebusiness030217 neurology & neurosurgery
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Treatment Monitoring Program for Implementation of Adherence to Second-Line Erlotinib for Advanced Non–Small-Cell Lung Cancer

2012

Abstract Background Adherence to erlotinib could be a determinant for clinical outcome and treatment toxicity in patients with advanced non–small-cell lung cancer (A-NSCLC). Patients and Methods In an observational study, the Basel Assessment of Adherence Scale (BAAS), a visual analogue scale (VAS), pill counting, and missed appointment rate were used to evaluate adherence in a first cohort of patients who was prescribed erlotinib without a specifically designed management strategy and in a second cohort of patients followed by an oral treatment monitoring program. Results Adherence > 95% by BAAS at 2 months of treatment in the first and second cohorts was 72% and 84%, respectively ( P = .0…

AdultMalePulmonary and Respiratory MedicineCancer Researchmedicine.medical_specialtyLung NeoplasmsVisual analogue scaleAdenocarcinomaMedication AdherenceErlotinib HydrochlorideCarcinoma Non-Small-Cell LungInternal medicinemedicineHumansErlotinib HydrochlorideProtein Kinase InhibitorsSurvival rateAgedNeoplasm StagingRetrospective StudiesAged 80 and overSalvage Therapybusiness.industryHealth Plan ImplementationRetrospective cohort studyAdenocarcinoma Bronchiolo-AlveolarMiddle AgedPrognosisSmall Cell Lung CarcinomaMonitoring programConfidence intervalSurgerySurvival RateOncologyCohortQuinazolinesCarcinoma Large CellPatient ComplianceFemaleErlotinibDrug MonitoringbusinessFollow-Up Studiesmedicine.drugClinical Lung Cancer
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Liking for fat is associated with sociodemographic, psychological, lifestyle and health characteristics

2014

Sensory liking influences dietary behaviour, but little is known about specifically associated individual profiles. The aim of the present study was to investigate the associations between liking for fat-and-salt and fat-and-sweet sensations and sociodemographic, economic, psychological, lifestyle and health characteristics in a large sample. Individual characteristics and liking scores were collected by a questionnaire among 37 181 French adults. Liking scores were constructed using a validated preference questionnaire. Multinomial logistic regression models were used to assess the associations between liking levels and individual characteristics. In both sexes, subjects belonging to low-l…

AdultMaleRisklikingAdolescent[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionhabitude alimentairesociodemographic factorsMedicine (miscellaneous)enquêteHyperphagiapsychological factorsBody Mass IndexCohort StudiesFood PreferencesYoung AdultSurveys and Questionnaires[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyfatSensationHumansObesitysantéLife StyleAgedMultinomial logistic regressionAged 80 and overInternetNutrition and DieteticssociologieCognitionMiddle AgedDietary FatssociodémographiePreferenceLarge sampleobésitéSocioeconomic FactorsFemaleObese subjectsFrancedietary determinantsPsychology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up StudiesClinical psychology
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German validation of the conners adult ADHD rating scale-self-report: confirmation of factor structure in a large sample of participants with ADHD.

2013

Objective: The Conners Adult ADHD Rating Scales (CAARS) assess symptoms specific to adults that are frequently used and have been translated into German. The current study tests the factor structure of the CAARS in a large sample of German adults with ADHD and compares the means of the CAARS subscales with those of healthy German participants. Method: CAARS were completed by 466 participants with ADHD and 851 healthy control participants. Confirmatory factor analysis was used to establish model fit with the American original. Comparisons between participants with ADHD and healthy controls and influences of gender, age, and degree of education were analyzed. Results: Confirmatory factor anal…

AdultMalemedicine.medical_specialtyMedizinFactor structurebehavioral disciplines and activitiesGermanConners Adult ADHD Rating Scales (CAARS)diagnostic issuesRating scaleGermanyHealthy controlmental disordersDevelopmental and Educational Psychologymedicineadult ADHD assessmentADHDHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersPsychiatrySelf reportadult ADHDMiddle AgedConfirmatory factor analysislanguage.human_languageLarge sampleClinical PsychologyAttention Deficit Disorder with HyperactivitylanguageFemaleSelf ReportPsychologyJournal of attention disorders
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Panoramic and skull imaging may aid in the identification of multiple myeloma lesions

2018

Background The purpose of this study was to investigate the presence of punched-out lesions in craniofacial bones using three different radiographic protocols in a large cohort of patients. Material and Methods One hundred fifty-five MM patients were evaluated using panoramic and skull (frontal and lateral) radiographs, which were performed in all patients at the time of MM diagnosis. The diagnostic potential for detecting punched-out lesions was compared among the radiographic techniques. Results MM punched-out lesions were identified in 135 (87%) panoramic radiographs, 141 (91%) frontal and 144 (93%) lateral skull radiographs. Punched out-lesions were synchronously present in skull and ja…

AdultMalemedicine.medical_specialtyRadiographyBone NeoplasmsFacial Bones03 medical and health sciences0302 clinical medicineRadiography PanoramicmedicineHumansNEOPLASIAS DE CABEÇA E PESCOÇOCraniofacialGeneral DentistryMultiple myelomaAgedRetrospective StudiesAged 80 and overOral Medicine and Pathologyintegumentary systembusiness.industryResearchSkull030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseLarge cohortSkullCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyBone lesion030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASFemaleSurgeryRadiologyDetection rateMultiple MyelomabusinessMedicina Oral Patología Oral y Cirugia Bucal
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Prevalence and treatment of cancer pain in Italian oncological wards centres: a cross-sectional survey.

2008

The aim of this national cross-sectional survey was to draw information on pain prevalence and intensity from a large sample of patients who were admitted to oncologic centres for different reasons and to evaluate the pain treatment and possible influencing factors.A total of 2,655 patients completed the study. Nine hundred and one patients (34%) reported pain.Higher pain levels were observed in inpatients, in the presence of bone metastases, and with low levels of Eastern Cooperative Oncology Group status. The number of patients receiving strong opioids increased with the highest levels of pain. However, a significant part of patients with moderate-severe pain were not receiving appropriat…

AdultMalemedicine.medical_specialtySettore MED/06 - Oncologia MedicaCross-sectional studyPain medicineMEDLINEPainSeverity of Illness IndexNeoplasmsOncology Service HospitalEpidemiologySeverity of illnessmedicinePrevalenceHumansAgedAged 80 and overPrimary Health Carebusiness.industryCancer painEpidemiologyOpioidsNursing researchPhysicians FamilyMiddle AgedLarge sampleAnalgesics OpioidCross-Sectional StudiesOncologyItalyFamily medicineHealth Care SurveysPhysical therapyFemaleCancer painbusinessSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
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The Usefulness of Dermoscopy for the Recognition of Malignant Collision Tumors.

2021

<b><i>Background:</i></b> Preoperative diagnosis of malignant collision tumors (MCT) is extremely difficult. The value of dermoscopy to improve the correct detection of these tumors has not been previously studied. This study aims to evaluate the diagnostic accuracy of MCT with and without dermoscopy and to describe the dermoscopic features of a large series of MCT. <b><i>Methods:</i></b> Dermoscopic images of 161 MCT were evaluated. Clinical and dermoscopic images of histopathologically proven MCT intermingled with other tumors were randomly presented to clinicians with different levels of experience, blinded to the diagnosis and objective of…

AdultMalemedicine.medical_specialtySkin NeoplasmsKeratosisDiagnostic accuracyDermoscopyDermatologySensitivity and SpecificityDiagnosis DifferentialYoung AdultSquamous cell carcinomaMedicineNevusHumansCollision tumorBasal cellBasal cell carcinomaMedical diagnosisKeratosis SeborrheicMelanomaPhysical ExaminationAgedAged 80 and overNevus Pigmentedbusiness.industryMelanomaLarge seriesMiddle Agedmedicine.diseaseCarcinoma Basal CellBasal cell carcinomaFemaleCollision tumorsRadiologybusinessDermatology (Basel, Switzerland)
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Large left ventricular metastatis in patient with liposarcoma.

2014

Abstract Metastasis to the heart and pericardium are rare. We present a 44-year-old male with pleural dedifferentiated liposarcoma and multiple metastases, with no previous cardiological history and/or cardiac symptoms. A transthoracic echocardiogram during the advanced stage of disease showed a lobulated, large and mobile mass, with homogeneous echogenicity, attached to the basal posterior wall of the left ventricle via a broad base and with intracavitary growth. This mass extends to inferolateral and inferoseptal wall of the left ventricle.

AdultMalemedicine.medical_specialtyTime FactorsLarge left ventricular metastasiBiopsyHeart VentriclesPleural Neoplasms030204 cardiovascular system & hematologyDoppler echocardiographyLiposarcomaMetastasisHeart Neoplasms03 medical and health sciencesFatal Outcome0302 clinical medicineHumansMedicinePericardium030212 general & internal medicinePleural Neoplasmheart metastases liposarcomamedicine.diagnostic_testbusiness.industryEchogenicityGeneral Medicinemedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareEchocardiography DopplerTumor Burdenmedicine.anatomical_structureVentricleliposarcomaDisease Progressioncardiovascular systemRadiologyTransthoracic echocardiogramTomography X-Ray ComputedCardiology and Cardiovascular Medicinebusiness
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Echocardiographic reference ranges for normal left ventricular layer-specific strain: results from the EACVI NORRE study

2020

Abstract Aims  To obtain the normal range for 2D echocardiographic (2DE) measurements of left ventricular (LV) layer-specific strain from a large group of healthy volunteers of both genders over a wide range of ages. Methods and results  A total of 287 (109 men, mean age: 46 ± 14 years) healthy subjects were enrolled at 22 collaborating institutions of the EACVI Normal Reference Ranges for Echocardiography (NORRE) study. Layer-specific strain was analysed from the apical two-, three-, and four-chamber views using 2DE software. The lowest values of layer-specific strain calculated as ±1.96 standard deviations from the mean were −15.0% in men and −15.6% in women for epicardial strain, −16.8% …

AdultMalemedicine.medical_specialtyadult echocardiographydeformation imagingHeart Ventricles030204 cardiovascular system & hematologyVentricular Function LeftReference values2D echocardiography03 medical and health sciences0302 clinical medicine[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicinereference values.Healthy volunteersmedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineEndocardiumNormal rangeStrain (chemistry)business.industryMyocardiumHealthy subjectsreference valueMean ageGeneral MedicineMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREMiddle AgedApex (geometry)EchocardiographyCardiology[SDV.IB]Life Sciences [q-bio]/BioengineeringFemalebusinessLarge groupCardiology and Cardiovascular MedicineEndocardiumHuman
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Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults

2021

ABSTRACTObjectivesThere is limited information comparing SARS-CoV-2 RNA load in the upper respiratory tract (URT) between children and adults, either presenting with COVID-19 or asymptomatic. Here we conducted a retrospective, single center study involving a large cohort of SARS-CoV-2 infected individuals to address this issue.Patients and MethodsA total of 1,184 consecutive subjects (256 children and 928 adults) testing positive for SARS-COV-2 RNA in nasopharyngeal exudates (NP) were included, of whom 424 (121 children and 303 adults) had COVID-19 not requiring hospitalization and 760 (135 children and 625 adults) were asymptomatic close contacts of COVID-19 patients. SARS-CoV-2 RNA testin…

AdultMicrobiology (medical)medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationSingle CenterAsymptomaticGastroenterologychildrenNasopharynxInternal medicinemedicineSingle specimenAdultsHumansViral sheddingChildeducationAsymptomatic InfectionsRetrospective Studieseducation.field_of_studySARS-CoV-2business.industryCOVID-19RNAGeneral MedicineViral LoadSARS-CoV-2 RNALarge cohortInfectious Diseasesmedicine.anatomical_structureRNA ViralOriginal Articlemedicine.symptombusinessViral loadUpper respiratory tractRespiratory tractClinical Microbiology and Infection
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